Porous Graphitic Carbon (PGC) is a unique stationary phase composed of flat sheets of hexagonally arranged carbon atoms with a satisfied valence, as in a very large polynuclear aromatic molecule. Hypercarb is unlike traditional silica bonded phases in both its structure and retentive properties, allowing for total pH stability and the retention and separation of highly polar species. Hypercarb columns are ideally suited to solve “problem” separations, in both reversed phase and normal phase HPLC and LC/MS applications.