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Shimadzu - LC-2010HT

Manufactured by  Shimadzu
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A new look, new concept HPLC. Shimadzu presents the LC-2010HT series of completely integrated, high throughput HPLCs.

The LC-2010HT is a next-generation HPLC based on the concept of high-throughput analysis and automated validation. The LC-2010HT is comprised of a degassing unit, quaternary low-pressure gradient unit, pump unit, mixer, ultra fast autosampler, column oven, and a UV-VIS detector with a thermostatted flow cell. System reliability has been further improved by standardizing the flow line arrangement in order to integrate the units. As with its predecessor, the LC-2010, the LC-2010HT has unparalleled flow rate and gradient concentration accuracy, but now boasts near-zero sample carryover with its needle coating technology. The LC-2010HT is available in two models, the standard model (LC-2010AHT) and the sample-cooled model (LC-2010CHT), for use across a broad range of applications from conventional liquid chromatography to semi-micro liquid chromatography.  
  
The latest technology for multiple samples, high-speed injection, and automation is now condensed into a compact package! This is the optimum HPLC for high-throughput analysis, whether for R&D, manufacturing, or product quality control. The Shimadzu LC-2010HT series meets the demand.
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Features of LC-2010HT

Large sample capacity   The LC-2010HT can handle up to 350 1mL vials or 210 1.5mL vials1 . When microtiter plate racks are used, up to 4 microtiter plates can be accommodated for continuous analysis of max. 1,536 samples.2 Deep Well plates can also be used. Two separate sample racks are used so that you can load samples in a rack while analyses are performed on samples from   the other rack.  

High-speed injection   Injection time per sample has been greatly reduced. Just 15 seconds* are required from start to finish for unheard of high-speed sample injection.  

High-speed analysis   Seven analyses are completed in 15 minutes thanks to high-speed injection and an ultra-fast column! This enables major improvements in analysis throughput in the field of drug discovery.  

Database   Multiple data are managed in one block with optional CLASS-Agent Manager*. Required data can be easily retrieved from a mass of data as analysis data is automatically loaded into the database.

General Specifications
Depth 500 mm
DetectorUV
Height605 mm
Width 430 mm
Power Requirements AC 100V-240V, 50/60Hz
Peak Power700 VA
Weight52 kg
Additional Specifications

Pump  
Pump Type: Serial dual plunger, micro volume (10µL on primary side, 5µL on secondary)  
Flow Rate: 0.001-5mL/min [1.0-35MPa / 145-5076psi]  
Flow Rate Accuracy: ±1% or ±2µL/min, whichever is larger (1mL/min, 3-10.0MPa / 435-1450psi, water, ambient temperature at 20°C, except in gradient solvent delivery),±2% or ±2µL/min, whichever is larger (except above condition and in gradient solvent delivery)  
Flow Rate Precision: ±0.075% RSD or 0.02minSD, whichever is larger (0.05-2mL/min, 1.0-3.5MPa / 145-5076psi, methanol, ambient temperature at 20°C  
Pressure Display Accuracy ±2% or ±0.5MPa, whichever is larger  
  
Degasser  
Type: Membrane on-line degasser, 5 lines (4x mobile phase, 1x autosampler rinsing liquid)  
Volume: 4mL/min for mobile phases, 2mL/line for autosampler rinsing liquid  
  
Autosampler  
Injection Method: Full volume injection, variable injection possible (no sample loss)  
Injection Volume: 0.1 - 100µL (standard), 1-2000µL (optional)  
(0.1-0.9µL in 0.1µL step, 1-2000µL in 1 µL step)  
Sample Capacity:   
1 mL vials: 350  
1.5mL vials: 140   
4mL vials: 100  
Microtiter Plates: Max. 4 plates (up to 384 samples with 96 well or 1536 samples with 384 well plates)  
Deep Well Plates: Max. 4 plates (up to 384 samples with 96 well plates)  
Injection Volume Repeatability: RSD <0.3% (10µL injection)  
Carryover: 0.01% (under conditions determined by Shimadzu)  
Injection Volume Accuracy: ±1% (50µL, n=6)  
Repetition Injection Frequency: 1-99/sample  
Analytical Run Time Setting: 0.01-9999.9 min (0.01 min step)  
Injection Condition Steps: Max. 202 steps  
Operating Pressure: 35.0MPa maximum  
Rinsing Liquid Degassing: Standard  
  
Column Oven  
Type: Block heating with preheating of the mobile phase  
Temperature Setting Range: 4-60°C, 1°C step  
Temperature Control Precision: ±0.1°C  
Temperature Control Range: (Ambient temperature -15°C) - 60°C  
Columns accommodated: 2 x 250mm columns  
Preheater volume: 4µL (for Semi-micro), and 9µL, 2 channels  
  
UV Detector  
Light Source: Deterium lamp, Low pressure mercury lamp (for wavelength accuracy check)  
Wavelength Range: 190-600nm  
Bandwidth: 8nm  
Wavelength Accuracy: ±1nm  
Wavelength Reproducibility: ±0.1nm  
Cell: 10mm, 8µL  
Cell Temperature Control: Standard (Setting temperature: High, Low, and OFF, 3 steps)  
Drift: 1 x 10-4AU/h (250nm, air in cell, constant room temperature)*  
Noise Level: ±0.25 x 10-5 AU (2 sec. time constant, 250nm, air in cell)*  
Linearity: ~ 2.5AU  
Simultaneous Dual Wavelenth Measurement: Selectable, two wavelengths in 190 - 370nm or 371 - 600nm  
Signal Output: 2 channels  
  
Automation Function: Auto start-up, Auto shut-down, Baseline stability autojudgement, Auto validation (Wavelength, Lamp Energy, Solvent delivery plusation, Column Temperature, Absorbance, Baseline drift, Baseline noise, Pressure Limit, Gradient accuracy)  
Auto purge, Cell auto recognition, Column management (option)  
Memory check, Max/Min pressure, Oven max. temperature, Lamp current, Motor Revolution monitor, Leak Sensor, Lamp Cover Sensor, Lamp housing max. temperature  
Application Solvent Organic solvents (except fluorine organic solvent, e.g. HFIPA), Aqueos solution and mixture of diluted acid or base (except halo-acids, e.g. hydrochloric acid)  
  
pH Range: 1-13 standard  
Liquid Contact Surface Materials: SUS316, Ruby, Sapphire, Teflon®, Hasteloy C, PEEK, Trifluoroethylene, PFA Perfluoroelastomer, Quartz, Ceramic  
Operating Ambient Temperature Range, Humidity: 4-35°C; max. 80% humidity  
Power Requirements   
  
*Condition according to ASTM E1657-96

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