• Membrane Test calculates Ra and Cm per sweep during a recording  
• Membrane and Seal Tests combined into a single resizable window  
• Support for four stimulus waveforms (with the Digidata 1440A)  
• Control of eight digital outputs per epoch during a sweep  
• Control of split-clock sampling per epoch during a sweep  
• Leak subtraction automatically saves both raw and corrected traces  
• All protocol durations are entered in time units  
• Support of the new Digidata 1440A digitizer  
• Support of the new Axoclamp 900A amplifier  
• New ABF 2.0 file format  

Existing functionality includes the ability to automate the execution of protocols, a variety of recording modes from continuous to waveform stimulation, online filtering and leak subtraction, and online statistics/graphs.  

AxoScope 10 provides a convenient way to produce background recordings with the included MiniDigi 2-channel digitizer*. You can monitor cells during intra-sweep periods, or create an overview of the entire day's activities including voice tags  

Clampfit 10 is a powerful solution for analyzing, graphing and layout of all of your Clampex and AxoScope data. Clampfit includes an extensive array of filtering and fitting routines. Functionality includes I-V graphs, power spectrums, and special "linked data views" for threshold (AP), template (minis) and single-channel modes of event detection and analysis.  

Applications   pCLAMP 10 is suitable for a wide variety of applications, ranging from electrophysiology to general physiology, from individual cells to networked cells, and from low-noise patch clamping to high-speed sodium channels.  

Uses:  

• Action Potentials (APs)  
• Current-clamp  
• Electromyography (EMG)  
• Electrooculography (EOG)  
• Excitatory Post-Synaptic Currents (EPSCs)  
• Excitatory Post-Synaptic Potentials (EPSPs)  
• Inhibitory Post-Synaptic Currents (IPSCs)  
• Inhibitory Post-Synaptic Potentials (IPSPs)  
• Long-Term Depression (LTD)  
• Long-Term Potentiation (LTP)  
• Miniature excitatory potentials (Minis)  
• Ratio dyes (with PMTs)  
• Single-channels  
• Slices  
• Spike trains  
• Synaptic networks  
• Voltage-clamp  
• Whole-cell