Molecular Devices - ImageXpress Ultra Confocal System

Manufactured by  Molecular Devices
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True point-scanning confocal System

ImageXpress® Ultra System offers the ultimate solution when crisp, clear images are a priority. Under control of state-of-the-art MetaXpress® Software, research-quality images of fixed- or live-cell assays are captured with the best possible resolution. Diverse samples can be imaged with excellent signal-to-noise, even when there is a high background, as in homogeneous, no wash assays, or when samples are thick such as tissue sections or neurons growing in matrix.
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Features of ImageXpress Ultra Confocal System
  • True laser scanning confocal system ensures a diverse set of samples can be imaged with excellent signal-to-noise ratio. 
  • Software configurable detection pinhole provides two orders of magnitude of Z-resolution flexibility ( 100 um) over fixed pinhole confocal systems.  
  • Simultaneous or sequential scanning with up to 4 solid state lasers facilitates simultaneous acquisition for optimal speed performance (up to 4 times faster) or unique sequential scanning in combination with high resolution z-offset to correct for objective lens induced chromatic aberrations. 
  • Fully automated 100 nm resolution voice coil driven stages provide positioning accuracy to capture intricate sub-cellular features as well as monitor long structures, such as neurons, across high resolution tiled or stitched images. 
  • Software configurable field-of-view simplifies imaging of large objects like model organisms (c. elegans and zebrafish) and long structures similar to neuronal processes.  
  • Industry-leading autofocus option provides fast, reliable focusing with a dedicated 690 nm focus laser and ultra-fast sensors that will not bleach your sample while decreasing read times up to 5-fold. 
  • Custom design for screening enables capturing 25,000 wells per day in a 384-well microplate assay with a two color high quality assay (e.g., Transfluor ® beta-arrestin translocation assay). Lower resolution assays can be performed in excess of 100,000 wells / day. 
  • 4-position automated objective changer eliminates manual objective changes and allows automated switching of magnifications during a single experiment.  
  • Universal plate holder facilitates image acquisition using any clear bottom plate from 6-well to 1536-well, in standard height, low profile, or low volume. 
  • Walk-away, 24/7 automation is achieved with the Thermo CRS CataLyst Express robotic plate handling system, enabling users to schedule multiple runs of one to three batches of 15 plates.
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