The Ultimate in High Separation Performance  

The ability to reliably perform the high-separation, high-sensitivity detection of trace compounds is required. Improving separation performance by simply increasing the column length also increases the analysis time, which reduces analysis efficiency.   With the Prominence UFLC, high-speed analysis was possible while maintaining a high degree of analysis accuracy and reliability. The Prominence UFLCXR offers greater separation performance. In order to achieve the ultimate in high separation performance, column efficiency has been improved by optimizing the balance between the particle diameter of the XR-ODS high-speed separation column and the column length, and the system has been optimized (pressure resistance: 66 MPa) to attain the highest possible level of column performance.  

The results obtained in the analysis of seven alkylphenones are shown below. The Prominence UFLCXR demonstrated a level of separation performance equivalent to that of at least a 250-mm (5-µm) column. The analysis time was a quarter of that required by a general-purpose LC, indicating that both high separation performance and high speed were achieved.  

Excellent Reproducibility and Low Sample Carryover  

Of the basic performance specifications required of analytical instruments, high reproducibility and low sample carryover are particularly important, and are essential for high-separation, high-sensitivity analysis.  

With Prominence, these needs were addressed at an early stage, and superior technology was cultivated for all the fundamental elements. This included a high-performance pump, an autosampler capable of a high level of injection reproducibility, even for minute quantities, and an injection mechanism that prevents sample carryover. These technologies have all been inherited by the Prominence UFLCXR, and support high-separation, high-sensitivity analysis.  

XR-ODS II High-Separation Column  

The Shim-pack XR-ODS, which was developed with the aim of increasing the speed attained under standard column pressure conditions, has been joined by the Shim-pack XR-ODS II, which was developed in order to facilitate high-speed, high-separation analysis for a wider range of applications, such as those involving methanol mobile phases, by using a new long column.  

The Shim-pack XR-ODS II is a high-separation analysis column that is suited to use in combination with the Prominence UFLCXR and that can also be used for high-temperature analysis.  

Reducing the particle size of the packing material to an optimum level and unifying the particle diameter help suppress flow resistance and ensure excellent stability. As with the Shim-pack XR-ODS, quality control is performed in accordance with the standards indicated in the quality assurance document provided with the column.