The most versatile and accurate particle sizing and counting analyzer available today. Using The Coulter Principle, also known as ESZ (Electrical Sensing Zone Method), the Multisizer 3 COULTER COUNTER provides number, volume, mass and surface area size distributions in one measurement, with an overall sizing range of 0.4 µm to 1,200 µm. Its response is unaffected by particle color, shape, composition or refractive index. The Coulter Principle is the absolute leading technology in high resolution and accuracy and it is further enhanced in the Multisizer 3 by using a Digital Pulse Processor (DPP). You will get the ultra-high resolution, multiple channel analysis and accuracy not provided by any other technology. It all makes the Multisizer 3 indispensable for any industrial or life science research project involving sizing and/or counting. Equally a powerful tool for quality control, it provides the analyst with a system which is easy to use, yet so technologically advanced that it is able to solve most particle sizing problems.
Proven technology Superior instrument design Quality assurance friendly Digital Pulse Processor (DPP) Easy to operate, user-friendly software Resolution can be selected from 4 to 300 channels at any selected range
|Interface||TCP/IP connection from analyzer to IBM compatible PC, running Windows 95, 98, 2000, NT 4.0|
|Size||0.4 to 1200 µm|
|Power Requirements||100 - 120V AC ± 10% 50/60 Hz, 220 -240V AC ± 10% 50/60 Hz|
|Peak Power||250 W|
a year ago
Recently, when we use the machine, There are two error messages (Loadmenu failed (1200) and dialogbox failed (1372) appeared frequently. Does anyone know what those messages stand for?
5 years ago
|Microbubble Sizing compared to Light Scattering sizing|
I understand sizing with multisizer M3 has a different measurement principle than light scattering. I am comparing those 2 tools (using the side scatter from a flow cytometer to size bubbles and compare it with coulter m3.
I have also noticed differences between in multisizers and accusizers (figure 2 on this link http://www.thno.org/v03/p0409/thnov03p0409s1.pdf). Can anyone provide a source with an explanation or analysis about why are the size histograms different for the same group of bubbles? Are there any sources that compare 2 devices using contrast agents? Both systems have overpressure to move the bubbles inside, but what else may be affecting the distributions so they are not identical?
Other than the inherent noise of the coulter m3 near the smallest size it can measure there is usually a difference in the size distributions specifically well above the noise and also extra tails that I see from m3. The light scattering technique always gives me narrower distributions than the coulter. Although both machines yield repeatable results (very precise instruments) their means are shifted and the distribution looks a little difference. If anyone has ideas about light scattering sizing vs multisizer sizing that would be very helpful!
5 years ago
|MS3 concentration reading problems|
These past few months, seemingly randomly, my samples would show an unusually high concentration (>90%) when I preview the sample. The concentration readings remain the same no matter how much I dilute it.
It should be mentioned in the plot that is displayed below the concentration bar shows a linear plot, as opposed to various peaks that normally occurs when concentration readings are working in.
The only troubleshooting I've been able to do is uninstall the aperture tube, install a DIFFERENT aperture tube only to uninstall it and reinstall the initial aperture tube. It is a redundant process.
The service at Beckman Coulter have not been unenthusiastic as we do not have warranty on the instrument. In fact, a tech came in to replace the expensive motherboard, which was initially perceived as the problem, only to have the problem persist.
Any recommendations or thoughts would be appreciated.