Uncompromising Performance 

Ultrahigh resolution up to 500,000 FWHM removes interferences  Precursor selection using a quadrupole mass filter allows the ion trap and Orbitrap mass analyzers to operate in parallel for excellent sensitivity and selectivity  Multiple dissociation techniques—CID, HCD, and optional ETD—with ion trap or Orbitrap detection at any level of MSn maximize flexibility for research applications  Flexibility of fragmentation—CID-HCD, HCD-CID, and HCD-HCD—at any stage of MSn analysis with fragment ions detected by either mass analyzer enables detailed structure determination of metabolites, glycans and other small molecules  Active beam guide with axial field reduces noise and increases robustness  Novel Orbitrap analyzer design and dual-pressure ion trap configuration provide fast MS/MS scan rates up to 20 Hz with unmatched spectral quality  Thermo Scientific™ Easy-Max NG™ and optional Thermo Scientific™ Ion Max NG™ and Nanospray Flex NG™ ion sources deliver next-generation performance 

Unrivaled Proteomics Capabilities 

Wide dynamic range and ultrahigh mass resolution allow identification of more low-abundance proteins with confidence  Ultrahigh mass resolution is ideal for analysis of monoclonal antibodies and other intact proteins  Sub-1-ppm mass accuracy provided by the optional Thermo Scientific™ EASY-IC™ ion source with internal calibration adds confidence to protein quantification results  Automated Synchronous Precursor Selection (SPS) for MS3 significantly increases the number of peptides and proteins identified and improves quantitative accuracy when using isobaric mass tags  Simple, reliable Thermo Scientific™ EASY-ETD™ ion source (optional) complements CID and HCD data and enhances characterization of complex P™s  Fast scanning yields more MSn data from a single run, enabling accurate structural characterization on a UHPLC timescale 

Easy-to-Use 

Dynamic Scan Management helps users get the maximum information from samples with ease, scheduling scan events most efficiently and intelligently matching each precursor with the optimum fragmentation mode and mass analyzer  A library of templates with application-specific defaults for common experiments simplifies method development  Compatibility with Thermo Scientific™ Compound Discoverer™, Mass Frontier™, Pinpoint™, Protein Deconvolution, Proteome Discoverer™, ProSightPC, and SIEVE™ software for increased productivity in specific applications