The Ion GeneStudio S5 Plus System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. From genes to exomes, the Ion GeneStudio S5 Plus System is designed to enable flexibility to help labs manage small and large projects across multiple applications. With cartridge-based reagents, the system is simple to use and offers scalability and flexibility. It uses Ion 5 Series chips to support a broad range of high-throughput sequencing for clinical research and research applications from microbial genomes and gene panels to exomes and transcriptomes. Key features: • Select the chip (Ion 510–550 chip) that fits your application and throughput needs to achieve from 2–130 million reads per run • Reduce setup time and complexity with cartridge-based plug-and-play reagents • Complete run and analysis in hours and move forward with your experiments
The Ion GeneStudio S5 Series The Ion GeneStudio S5 Series sequencers share the same foundational technology and fluidic architecture across all three instruments: the Ion GeneStudio S5 System, this Ion GeneStudio S5 Plus System, and Ion GeneStudio S5 Prime System. The primary difference across the three instruments is on-sequencer analysis time. Speed The Ion GeneStudio S5 Series leverages the speed of semiconductor sequencing to enable the production of high quality sequencing data in a few hours and enables you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time when paired with the Ion Chef System. Simplicity With single-day installation, a straightforward user interface, and cartridge-based reagents, the Ion GeneStudio S5 Series sequencers are easy to use. Combined with Ion AmpliSeq technology for target selection, the Ion Chef System for automated library and template preparation, and Ion Reporter Software for automated variant annotation, targeted sequencing is simpler than ever. Small sample input Low input DNA from challenging samples types such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competitor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion GeneStudio S5 Series, you can use as little as 1 ng input DNA or RNA. Scalability Why buy multiple systems for your lab when you can run all of your targeted sequencing or microbial applications on a single next-generation sequencer? The Ion 5 Series chips that run on the Ion GeneStudio S5 Series provide several throughput options, so your lab has the flexibility to scale from small to large projects, enabling multiple targeted sequencing applications on a single system. Simple analysis and storage solutions Torrent Suite Software and Ion Reporter Software make NGS easy for beginners and experts alike. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Thermo Fisher Cloud or local options available based on your needs).