Proteome Sciences - TMTcalibrator™

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Enhanced detection of tissue-derived biomarkers in body fluids typically not seen in standard MS workflow

Four-point calibration curve for statistical assessment of spectrum quality

Allows use of disease-related tissue or cells as surrogate biomarker donor to trigger MS and boost signal of equivalent marker in body fluid

Can be combined with a wide range of proteomic workflows e.g. phosphopeptide enrichment to truly maximize signal enhancement

Standardized data outputs in Excel and ‘TSV’ files

Automated annotation of biological features from UniProt KB, Entrez IDs and Reactome

Results in 4 weeks (based on a single TMT®10plex of 6 fluid samples plus 4 point calibrator)

Simple report highlighting key biological events enriched in the study

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Thu Nov 09 2017

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