The new generation of Eppendorf bottletop dispensers Varispenser 2 and Varispenser 2x show improvements in many details. Their tight seal provides best possible protection against contact with caustic media. They are chemically resistant and fully autoclavable. Especially for Varispenser 2x with recirculation valve, the new design allows for extracting reproducible dispensing volumes with no reagent waste. Drying tube for protection of reagents against humidity or spiral discharge tube for easy serial dispensing, complete the Varispenser 2 / 2x to provide a convenient system of bottletop dispensers for most routine liquid handling tasks.