Bruker Corporation - AVANCE-IVDr
Manufactured by Bruker Corporation
High Throughput NMR for Development and Validation of High-Quality and Cost-Effective IVD-by-NMR and Clinical Screening Assays
Standardized nuclear magnetic resonance (NMR) spectroscopy platform enabling cost-effective, high-performance NMR clinical screening and IVD-by-NMR discovery and validation of novel NMR assays. The new AVANCE IVDr system, presently for research use only, is a complete, proven and standardized platform for NMR clinical research and screening, as well as for IVD-by-NMR research.
The new standardized platform offers barcode analysis, control by a LIMS system, the high-throughput autosampler SampleJet™, remote access, and automatic analysis and customizable analytical result reporting.
Based on Bruker-validated SOPs, the AVANCE IVDr platform enables the development of diagnostic tools for body-fluids that can address a variety of medical questions. The SOPs guarantee the production of highly reproducible clinical data, enabling the exchange and validation of novel NMR assays between laboratories on a global basis. In a translational clinical research environment the results produced by these NMR assays can easily be transferred into clinical screening and future IVD use.
The new standardized platform offers barcode analysis, control by a LIMS system, the high-throughput autosampler SampleJet™, remote access, and automatic analysis and customizable analytical result reporting.
Based on Bruker-validated SOPs, the AVANCE IVDr platform enables the development of diagnostic tools for body-fluids that can address a variety of medical questions. The SOPs guarantee the production of highly reproducible clinical data, enabling the exchange and validation of novel NMR assays between laboratories on a global basis. In a translational clinical research environment the results produced by these NMR assays can easily be transferred into clinical screening and future IVD use.
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Features of AVANCE-IVDr
It features high sensitivity and information-rich output at 600 MHz proton-NMR frequency, and incorporates advanced hardware, software, automation, spectral libraries and standard operating procedures (SOPs) for high-performance biofluid screening and assay validation. Customer benefits include higher information content and spectral feature differentiation compared to low-field NMR systems, as well as excellent reproducibility, high throughput and potentially dramatically lower cost per sample for better clinical screening and IVD-by-NMR discovery and validation.
- Minimal sample preparation * Non-destructive measurement * Full automation in high throughput screening mode * Highest reproducibility and data quality from sample to sample and instrument to instrument * Quantification of large sets of metabolites with automated reporting * Classification and discriminiation using statistical tools with automated reporting * Low cost per sample and lowest cost per parameter, with small footprint to suit every lab
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