ÄKTAprime plus is a compact one-step purification system that operates with most prepacked columns. For reliability and convenience, we recommend HiTrap, HiPrep or HiLoad columns that simply snap on to the side of the unit. The system has preprogrammed methods for typical applications such as purification of affinity tagged proteins, MAbs and sample clean-up. The flexible system can be used for more general purification tasks such as buffer exchange, gel filtration, ion exchange, HIC, and affinity chromatography.   
   
The unit is compact and comprises a system pump, fraction collector, monitors for UV, conductivity and pH (optional). Valves for buffer selection, sample injection, gradient formation, and flow diversion are also integrated into the system. The system is not PC controlled but together with PrimeView software it offers continuous real-time monitoring and evaluation of results.