Beckman Coulter - Multisizer™ 4
Manufactured by Beckman Coulter

Beckman Coulter - Multisizer™ 4

Discover the most versatile and accurate particle sizing and counting analyzer on the market. Using the Coulter Principle, also known as Electrical Sensing Zone (ESZ), the Multisizer 4 COULTER COUNTER® provides size distributions in number, volume and surface area in one measurement, with an overall sizing range of 0.4 µm to 1600 µm. Its response is unaffected by particle color, shape, composition or refractive index. The Coulter Principle is the leading technology in high resolution and accuracy and it is enhanced even further in the Multisizer 4 by using a Digital Pulse Processor (DPP). DPP provides ultra-high resolution, multiple channel analysis and accuracy that is unattainable by other technologies. It all makes the Multisizer 4 indispensable for any research project involving sizing and/or counting. An equally powerful tool for quality control, the Multisizer 4 provides analysts with an easy-to-use system that is so technologically advanced, it can solve most particle sizing problems.


     • Increased dynamic range     • Increased resolution     • Proven technology     • Superior instrument design     • Quality assurance friendly     • Digital Pulse Processor (DPP)     • Dynamic size measurements     • Provides number, volume, mass and surface area size distributions in one measurement     • V-Check (IQ, OQ, PQ) instrument validation    

Temperature Range5 to 40 °C
Size0.4 to 1600 µm
Measurement Time 0.1 to 999 seconds, selectable in 10 ms increments. Typically, time analysis is 10 to 90 seconds.
Depth 24 in (excluding computer)
Height20 in (excluding computer)
Width 25 in (excluding computer)
Power Requirements Less than 55 volt-amps (watts)
Weight99 lbs (excluding computer)


3 years ago
Communication problem
Can't connect to Multisizer 4 via IP protocol.


  • Checked cable (tried another cable)
  • Checked PC NIC IP config
  • Checked software target IP (
  • Tried another computer with same software settings and same NIC IP settings (
  • Tried tcpdump (packet sniffing) on eth port from the PC and not receiving a single IP packet.
  • Tried router with DHCP server between computer and Multisizer: no DHCP lease given to Multisizer even after several reboots
  • Tried APIPA IP in case the Multisizer falls on APIPA: nothing
Anyone had same issue? Beckman Coulter tech crew offers me to buyNS486 Controller or Main control board. I hope someone had the same issue here and would tell me it was solved by replacing which part.



4 years ago
about size error

I want to measure the cell size, but recently the results are half as they should be. If the error is small, I can calibrate it. But if the values become half of the values before, should I still calibrate it? or there is something wrong in the machine that I can fix it. Thanks!



6 years ago
Particle Concentration
I am using the Multisizer 4 to test sediment particle sizefor research at the University of South Carolina. I am currently having an issue with the concentration of sediment. Before I have put any sediment into the beaker,the multisizeris reading a high concentration of particles in the beaker. The beaker is clean and I have cleaned the aperature several times so I am starting to think there is something wrong with the machine or I may be missing something (?).What could possibly be wrong besides the beaker and aperature not being cleanand is there anyway of fixing it myself without having to call in for assistance? We recently had to call in for assistanceon the multisizer for a different issue,which did not comeuntil a few weeks later so I was unable to run tests until a Beckman Coulter representative came and fixed the machine. Thanksfor any help!


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Beckman Coulter - Multisizer™ 4