Browse Equipment - Supplies and Consumables 968 Results
powerful functional assay to detect compound activity against known and/or orphan GPCR targets in a high content screening environment.Leveraging the principle that virtually all GPCRs rapidly undergo deactivation or "desensitization" by a common pathway, the Transfluor® Assay is a cell-based fluorescence assay used to screen for G-protein coupled receptor (GPCR) ligands and other p...Cell Culture Reagents The QBT™ Fatty Acid Uptake Assay is a single-step, homogeneous, fluorescent assay for monitoring the activity of fatty acid transport proteins.Conventional protocols for monitoring fatty acid uptake using radioactivity often require cell lysis and processing at very low temperature, making them expensive, slow and unsuitable for high throughput screening. Other fluorescence-based protocols ...Cell Culture Reagents The homogeneous Neurotransmitter Transporter Uptake Assay Kit provides a fast, simple, and reliable fluorescence-based assay for the detection of dopamine, norepinephrine, and serotonin transporter (DAT, NET and SERT, respectively) activity in expres... The homogeneous Neurotransmitter Transporter Uptake Assay Kit provides a fast, simple, and reliable fluorescence-based a...Cell Culture Reagents IMAP technology provides a non-radioactive, homogeneous assay for accurate determination of kinase, phosphatase, and phosphodiesterase activities.Until recently, assays of kinase activity have been performed using radioactive isotopes or highly specific antibodies. In contrast, IMAP® technology provides a non-radioactive, homogeneous assay applicable to a wide variety of kinases without regard...Cell Culture Reagents Broadest selection of calcium assay kits to address diversified GPCR and ion channel targetsFLIPR® Calcium Assay Kits (1, 3, 4, 5, 6 & 6-QF) provide the most comprehensive method for detecting intracellular calcium changes in a simple and reliable homogeneous assay format. Select from six formulations to complement your target of interest, ...Cell Culture Reagents Mix-and-read simplicity to rapidly screen ion channel targetsThe FLIPR® Membrane Potential Assay Kit enables observation of real-time membrane potential changes associated with ion channel activation and ion transporter proteins. Each homogeneous assay kit utilizes a proprietary indicator dye and quencher comb...Cell Culture Reagents Functional measurement of potassium channel activity in a cell-based assayThe FLIPR® Potassium Assay Kit measures functional activity of ligand- and voltage-gated potassium channels. The homogeneous, no-wash assay protocol provides a large signal window and high Z’ values.
The FLIPR Potassium Assay Kit exploits the perm...Assays The EarlyTox™ Cell Integrity Kit from Molecular Devices is a fluorescence-based cell viability assay integrated with the company’s existing hardware and software for quick IC50 analysis in adherent and non-adherent cells. The kit is equipped wi... The EarlyTox™ Cell Integrity Kit from Molecular Devices is a fluorescence-based cell viability assay integrated wi...Assays Predict toxicity earlierFor researchers looking to identify cardiotoxic compounds, the EarlyTox™ Cardiotoxicity Kit allows you to screen more compounds earlier in drug discovery. Now you can prioritize leads and direct medicinal chemistry efforts sooner, improving pro...Assays This kit enables the detection of an early apoptosis event based on the measurement of the glutathione content in live mammalian cells using a fluorescence microplate reader. Diminished cellular glutathione (GSH), which is an important anti-oxidant i... This kit enables the detection of an early apoptosis event based on the measurement of the glutathione content in live m...Analytical Reagent